"Doctor Knows Best"

Doctor knows best? The use of evidence in implementing self-directed support in health care (PDF)

Doctor knows best? The use of evidence in implementing self-directed support in health care

Genome Rearrangements: Mother Knows Best!

In Paramecium, developmentally programmed genome rearrangements can be altered by the presence of homologous sequences within the maternal somatic nucleus. Newly identified RNA-binding proteins appear to mediate the transfer of homologous sequence information from the maternal to the developing somatic nucleus, facilitating epigenetic regulation of this large-scale genome reorganization.

Have you seen ? “ Father knows best ? ” Ashley

Following fertilization, activation of a complex developmental program requires the differential expression of key genes. In most metazoa, the prevailing view is that early differential gene expression occurs primarily through post-transcriptional regulation of maternally deposited products in the oocyte. Two novel studies published from the Rajewsky laboratory in this issue of The EMBO Journal...

Mother knows best: maternal influence on early embryogenesis.